apalutamide will lower the level or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with medication that are CYP2C19 substrates may lead to lessen publicity to these drugs.Prescribers are strongly advised to just take all reasonable